Critical Appraisal Checklists for Systematic Reviews and Comprehensive Reviews

This is a version of the LibGuide I started while employed at Temple University Health Sciences Library from July 2015-September 12, 2022. I plan to maintain it here going forward.

Critical Appraisal Checklists

“Critical appraisal skills enable you to assess the trustworthiness, relevance and results of published papers so that you can decide if they are believable and useful.”  

(http://www.casp-uk.net/criticalappraisal)

Learn more about Critical Appraisal

  • How to Read a Paper by Trisha GreenhalghISBN: 9781119484745Publication Date: 2019-05-06

Critical Appraisal Checklists by specific Study Design type

Randomized Controlled Trials

ROB 2.0 Risk Of Bias Tool

There are 3 variations of the tool based on trial design.  Choose the appropriate version.

1.  Individually randomized, parallel group trials (traditional RCT)

2.  Cluster randomized, parallel group trials (like traditional but randomized by groups)

3.  Individual randomized, cross-over trials (randomization occurs to determine the order the patient receives both treatments)

https://www.riskofbias.info/welcome/rob-2-0-tool


CASP: Randomised Controlled Trial Appraisal Tool
Summary: Critical Appraisal Skills Program (CASP): RCT CAT is a methodological checklist which provides key criteria relevant to randomised controlled trials.
Authors: Public Health Resource Unit, NHS, England

http://media.wix.com/ugd/dded87_40b9ff0bf53840478331915a8ed8b2fb.pdf

Non-randomized Studies or Observational Studies:

ROBINS-I Risk of Bias for non-randomized (observational) studies or cohorts of Interventions

http://www.bristol.ac.uk/population-health-sciences/centres/cresyda/barr/riskofbias/robins-i/​

ROBINS-E Risk of Bias for non-randomized (observational) studies or cohorts of Exposures other than interventions, including environmental and occupational exposures

http://www.bristol.ac.uk/population-health-sciences/centres/cresyda/barr/riskofbias/robins-e/​

Newcastle-Ottawa scale (NOS) -most widely used for case control or cohort studies

http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp

IHE Case Series Studies Critical Appraisal Checklist

https://www.ihe.ca/research-programs/rmd/cssqac/cssqac-about

JBI Critical Appraisal Checklist for Case Series

https://wiki.joannabriggs.org/display/MANUAL/Appendix+7.3+Critical+appraisal+checklists+for+case+series

JBI Critical Appraisal Checklist for Case Reports

https://wiki.joannabriggs.org/display/MANUAL/Appendix+7.4+Critical+appraisal+checklist+for+case+reports

The Methodological Index for Non-Randomized Studies (MINOR) is a tool for assessing non-randomized interventional studies

This link will open a PDF document.  http://cobe.paginas.ufsc.br/files/2014/10/MINORS.pdf

Agency for Healthcare Research and Quality (AHRQ) methodological checklist for cross-sectional/prevalence studies

https://www.ncbi.nlm.nih.gov/books/NBK35156/#_A157879_

AXIS-To assess the quality of cross-sectional/prevalence studies

This link will open a PDF document. http://bmjopen.bmj.com/content/bmjopen/6/12/e011458.full.pdf

The TREND Statement
Summary: The TREND (Transparent Reporting of Evaluations with Nonrandomized Designs) statement is a 22-item checklist specifically developed to guide standardized reporting of nonrandomized controlled trials. 

http://www.cdc.gov/trendstatement/

The STROBE Statement

Strengthening the reporting of observational studies (cohort, case-control, and cross-sectional) 

http://www.strobe-statement.org/index.php?id=available-checklists

Mixed Methods Appraisal Tool (MMAT)-used for qualitative, quantitative, and/or mixed methods studies. Helpful for those working on a Mixed Methods Review. 

This link will open a PDF document. http://mixedmethodsappraisaltoolpublic.pbworks.com/

w/file/fetch/127916259/MMAT_2018_criteria-manual_2018-08-01_ENG.pdf

Public Health:

MetaQat – Meta-Tool for appraising all types of public health evidence

http://www.publichealthontario.ca/en/ServicesAndTools/Pages/Critical-Appraisal-Tool.aspx

Qualitative:

CanChild for qualitative reviews 

These links will open a PDF document. Guidelines and Form

Quantitative Research (Public Health Research)

EPHPP- Quality Assessment tool for Quantitative Studies 

Animal Research:

Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) risk of bias assessment tool for assessing animal studies

Article: http://www.ncbi.nlm.nih.gov/pubmed/24667063 

Checklist: https://www.radboudumc.nl/getmedia/60b8b9d8-84d7-4325-843c-6408cf065aca/SYRCLE-EFSA-course-1-okt-2016-(quality-assessment)_RoB-table.aspx

(invivo studies) Review the ARRIVE guidelines  

https://www.nc3rs.org.uk/arrive-guidelines

Critical Appraisal of Studies using Animal Models
http://ilarjournal.oxfordjournals.org/content/55/3/405.full.pdf+html

Diagnostic Accuracy

QUADAS-2

To evaluate the risk of bias and applicability of primary diagnostic accuracy studies.

This link will open a PDF document. http://www.bristol.ac.uk/media-library/sites/quadas/migrated/documents/quadas2.pdf


CASP: Diagnostic Test Studies  

This link will open a PDF document. http://media.wix.com/ugd/dded87_3815f02af1b34c21b8c3b2b5020024c3.pdf

Centre for Evidence Based Medicine (CEBM) Diagnosis Critical Appraisal Worksheet  

This link will open a PDF document. http://media.wix.com/ugd/dded87_3815f02af1b34c21b8c3b2b5020024c3.pdf

Library and Information Science Research

https://librarysearch.temple.edu/articles/emerald_s10-dot-1108-slash-07378830610692154

Grey Literature

Critical Appraisal of Clinical Practice Guidelines

AGREE II

International tool for the assessment of practice guidelines

Critical Appraisal of Systematic Reviews

ROBIS- A tool for assessing the risk of bias in systematic reviews. 

 http://www.bristol.ac.uk/social-community-medicine/projects/robis/robis-tool/

Joanna Briggs Critical Appraisal for Systematic Reviews Checklist-

This link will open a PDF document. https://joannabriggs.org/sites/default/files/2019-05/JBI_Critical_Appraisal-Checklist_for_Systematic_Reviews2017_0.pdf

AMSTAR 2-A Measurement Tool to Assess (quality assessment) of Systematic Reviews

http://amstar.ca/

Health-Evidence Appraisal Tool for Reviews

This link will open a PDF document. http://healthevidence.org/documents/our-appraisal-tools/QATool&Dictionary_01Jun16.pdf

AHRQ-Assessing the Risk of Bias in Systematic Reviews of Healthcare Interventions

https://effectivehealthcare.ahrq.gov/topics/methods-bias-update/methods

Critical Appraisal of a Mixed Methods Systematic ReviewThis link will open a PDF document.

Oops, if you find any broken links, please contact me!

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